KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
39.39
Human Site:
S358
Identified Species:
54.17
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S358
S
V
A
F
L
D
F
S
Q
D
E
L
G
D
P
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S358
S
V
A
F
L
D
F
S
Q
D
E
L
G
D
P
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
Q479
V
A
F
L
D
F
S
Q
D
E
L
G
D
P
L
Dog
Lupus familis
XP_543550
1017
111618
S358
S
V
A
F
L
D
F
S
Q
D
E
L
G
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
S358
S
V
A
F
L
D
F
S
Q
D
E
L
G
D
P
Rat
Rattus norvegicus
NP_001129232
1015
111665
S358
S
V
A
F
L
D
F
S
Q
D
E
L
G
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
S358
S
V
A
F
L
D
F
S
Q
D
E
L
G
D
P
Frog
Xenopus laevis
Q8QFR2
1013
112021
S358
S
V
A
Y
L
D
F
S
Q
D
E
L
G
D
P
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
S358
T
V
A
F
L
D
F
S
Q
D
E
L
G
D
P
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
S358
T
V
A
Y
L
D
F
S
L
D
E
L
G
D
P
Fruit Fly
Dros. melanogaster
O17468
1047
113397
T355
S
I
A
C
L
K
F
T
E
E
E
L
G
K
A
Honey Bee
Apis mellifera
XP_001122939
838
91355
E204
W
R
T
T
D
W
T
E
A
A
L
I
S
E
P
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
G301
Q
L
T
C
A
A
V
G
S
R
D
K
S
I
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
F330
T
A
S
A
R
P
L
F
V
A
R
H
F
F
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
D358
T
V
A
M
I
H
F
D
P
K
E
L
G
V
R
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
F206
D
D
R
T
M
K
I
F
R
Y
H
K
T
G
D
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
G356
D
L
A
W
T
P
D
G
Q
T
V
F
A
A
S
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
100
93.3
93.3
80
46.6
6.6
0
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
100
100
100
93.3
73.3
20
13.3
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
0
N.A.
40
0
13.3
P-Site Similarity:
N.A.
13.3
N.A.
53.3
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
71
6
6
6
0
0
6
12
0
0
6
6
6
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
6
0
0
12
53
6
6
6
53
6
0
6
53
6
% D
% Glu:
0
0
0
0
0
0
0
6
6
12
65
0
0
6
0
% E
% Phe:
0
0
6
42
0
6
65
12
0
0
0
6
6
6
0
% F
% Gly:
0
0
0
0
0
0
0
12
0
0
0
6
65
6
0
% G
% His:
0
0
0
0
0
6
0
0
0
0
6
6
0
0
0
% H
% Ile:
0
6
0
0
6
0
6
0
0
0
0
6
0
6
0
% I
% Lys:
0
0
0
0
0
12
0
0
0
6
0
12
0
6
0
% K
% Leu:
0
12
0
6
59
0
6
0
6
0
12
65
0
0
6
% L
% Met:
0
0
0
6
6
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
12
0
0
6
0
0
0
0
6
59
% P
% Gln:
6
0
0
0
0
0
0
6
53
0
0
0
0
0
0
% Q
% Arg:
0
6
6
0
6
0
0
0
6
6
6
0
0
0
6
% R
% Ser:
48
0
6
0
0
0
6
53
6
0
0
0
12
0
18
% S
% Thr:
24
0
12
12
6
0
6
6
0
6
0
0
6
0
0
% T
% Val:
6
59
0
0
0
0
6
0
6
0
6
0
0
6
0
% V
% Trp:
6
0
0
6
0
6
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _